10.1021/ol051335u.s001 Ken Tanaka Ken Tanaka Takeaki Shoji Takeaki Shoji Cationic Rhodium(I)/BINAP Complex-Catalyzed Isomerization of Secondary Propargylic Alcohols to α,β-Enones American Chemical Society 2005 propargylic alcohols Cationic selectivity intramolecular migration Rhodium cationic rhodium Enone variant Isomerization enone proceed pathway isomerization Secondary Propargylic Alcohols 2005-08-04 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Cationic_Rhodium_I_BINAP_Complex_Catalyzed_Isomerization_of_Secondary_Propargylic_Alcohols_to_Enones/3274633 We have developed a cationic rhodium(I)/BINAP complex-catalyzed isomerization of secondary propargylic alcohols to α,β-enones. The asymmetric variant of this reaction, a kinetic resolution of secondary propargylic alcohols, was also developed with good selectivity. The mechanistic study revealed that the isomerization proceeds through intramolecular 1,3- and 1,2-hydrogen migration pathways.