A Convenient Preparation of Xanthene Dyes
Youjun Yang
Jorge O. Escobedo
Alexander Wong
Corin M. Schowalter
Michael C. Touchy
Lijuan Jiao
William E. Crowe
Frank R. Fronczek
Robert M. Strongin
10.1021/jo051002a.s005
https://acs.figshare.com/articles/dataset/A_Convenient_Preparation_of_Xanthene_Dyes/3272203
A facile synthetic route utilizing readily available reagents affords a series of regioisomerically
pure xanthene dye derivatives. Advantages include relatively mild conditions and good to excellent
yields. Nonpolar, highly crystalline intermediates are isolable by standard chromatographic
techniques. The intermediates are in the requisite xanthene oxidation state, thus avoiding the
need for relatively inefficient oxidation chemistry and/or harsh conditions. During the course of
this work, a new boron-mediated 1,2-aryl migration reaction was discovered.
2005-08-19 00:00:00
Convenient Preparation
migration
xanthene oxidation state
technique
intermediate
Advantages
isolable
series
Nonpolar
regioisomerically
xanthene dye derivatives
reagent
Xanthene Dyes
yield
oxidation chemistry
aryl