%0 Journal Article
%A Liu, Yu
%A Liang, Peng
%A Chen, Yong
%A Zhao, Yan-Li
%A Ding, Fei
%A Yu, Ao
%D 2005
%T Spectrophotometric Study of Fluorescence Sensing and Selective Binding of Biochemical
Substrates by 2,2‘-Bridged Bis(β-cyclodextrin) and Its Water-Soluble Fullerene Conjugate
%U https://acs.figshare.com/articles/journal_contribution/Spectrophotometric_Study_of_Fluorescence_Sensing_and_Selective_Binding_of_Biochemical_Substrates_by_2_2_Bridged_Bis_i_i_cyclodextrin_and_Its_Water_Soluble_Fullerene_Conjugate/3251392
%R 10.1021/jp0527507.s001
%2 https://acs.figshare.com/ndownloader/files/5086762
%K Spectrophotometric Study
%K UV
%K Spectrophotomeric studies
%K hydroxyl side
%K Selective Binding
%K dichroism spectroscopy
%K fluorescence sensor
%K cleaving DNA
%K inclusion complexation behavior
%K fullerene conjugate 3 displays
%K cyclodextrin
%K conformation
%K precursor N
%K bi
%K Biochemical Substrates
%K substrate
%K NMR
%X A bis(β-cyclodextrin)−fullerene conjugate (3) linked at the secondary hydroxyl side was prepared in a good
yield from its precursor N,N‘-bis(2-(2-aminoethylamino)ethyl)malonamide-bridged bis(β-cyclodextrin) (2).
Spectrophotomeric studies on the conformation and the inclusion complexation behavior of 3 with a variety
of organic and biochemical substrates by means of UV−vis, FT-IR, NMR, fluorescence, and circular dichroism
spectroscopy showed that the bis(β-cyclodextrin)−fullerene conjugate displayed an intramolecular capsule-type conformation in aqueous solution. Because of the multiple binding of bis(β-cyclodextrin) with substrates,
2 can act as an efficient fluorescence sensor for biochemical substrates, while its fullerene conjugate 3 displays
a capability of cleaving DNA under visible-light irradiation.
%I ACS Publications