10.1021/jo052506b.s002
Grant R. Krow
Grant R.
Krow
Qiuli Huang
Qiuli
Huang
Guoliang Lin
Guoliang
Lin
Ryan A. Centafont
Ryan A.
Centafont
Andrew M. Thomas
Andrew M.
Thomas
Deepa Gandla
Deepa
Gandla
Charles DeBrosse
Charles
DeBrosse
Patrick J. Carroll
Patrick J.
Carroll
5-Carboxy-2-azabicyclo[2.1.1]hexanes as Precursors of 5-Halo,
Amino, Phenyl, and 2-Methoxycarbonylethyl Methanopyrrolidines
American Chemical Society
2006
stereoselectively
New
Ph
Bu
Bn
Phenyl
Br
Methoxycarbonylethyl
Halo
Carboxy
Precursor
syn
Methanopyrrolidine
NHCOOR
CH 2 CH 2 COOMe
Cl
carboxy substrate
Amino
2006-03-03 00:00:00
Dataset
https://acs.figshare.com/articles/dataset/5_Carboxy_2_azabicyclo_2_1_1_hexanes_as_Precursors_of_5_Halo_Amino_Phenyl_and_2_Methoxycarbonylethyl_Methanopyrrolidines/3235255
Novel 5-X-substituted-2-azabicyclo[2.1.1]hexanes (X = 5-<i>syn</i>-Cl, -Br, -I, -Ph, -NHCOOR (R = Me, Bn,
<i>t</i>-Bu), -CH<sub>2</sub>CH<sub>2</sub>COOMe and X = 5-<i>anti</i>-Br, -I, -Ph) were synthesized from the X = 5-<i>syn</i>-carboxy
derivative. New 5-<i>anti</i>-X-2-azabicyclo[2.1.1]hexanes, X = NHCOOR (R = Me, Bn), were prepared
stereoselectively from the X = 5-<i>anti</i>-carboxy substrate.