10.1021/acs.orglett.6b01027.s001 Yun Lin Yun Lin Xinglin Yang Xinglin Yang Weidong Pan Weidong Pan Yu Rao Yu Rao One-Step Synthesis of Diverse Pyridine-Containing Heterocycles with 3‑Ethoxycyclobutanones at Room Temperature American Chemical Society 2016 ambient temperature Heterocycle union Room Temperature heterocyclic compounds approach synthesis Lewis acid heterocycle regioselectivity Ethoxycyclobutanone heterocyclic amines ethoxycyclobutanone bioactive Diverse Synthesi 2016-04-26 15:36:34 Journal contribution https://acs.figshare.com/articles/journal_contribution/One_Step_Synthesis_of_Diverse_Pyridine_Containing_Heterocycles_with_3_Ethoxycyclobutanones_at_Room_Temperature/3201568 An efficient and convenient approach toward a diversity-oriented synthesis of bioactive pyridine-containing fused heterocycles is described. Through a Lewis acid catalyzed union of 3-ethoxycyclobutanones with various heterocyclic amines, a broad range of heterocyclic compounds were prepared readily at ambient temperature with excellent regioselectivity.