%0 Generic
%A Zhan, Miao
%A Li, Ren-Zhe
%A Mou, Ze-Dong
%A Cao, Chao-Guo
%A Liu, Jie
%A Chen, Yuan-Wei
%A Niu, Dawen
%D 2016
%T Silver-Assisted, Iridium-Catalyzed Allylation of Bis[(pinacolato)boryl]methane
Allows the Synthesis of Enantioenriched Homoallylic Organoboronic
Esters
%U https://acs.figshare.com/articles/dataset/Silver_Assisted_Iridium_Catalyzed_Allylation_of_Bis_pinacolato_boryl_methane_Allows_the_Synthesis_of_Enantioenriched_Homoallylic_Organoboronic_Esters/3201388
%R 10.1021/acscatal.6b00719.s002
%2 https://acs.figshare.com/ndownloader/files/5025421
%K presence
%K homoallylic organoboronic esters
%K Enantioenriched Homoallylic Organoboronic Esters Described
%K utility
%K silver salt
%K Allylation
%K Synthesi
%K CH
%K LiO t Bu
%K bi
%K Allow
%K title compounds
%K allylic carbonates
%K enantioselective approach
%K chiral organoboronates
%K Bis
%K conversion
%K allylation reactions
%X Described here is
an enantioselective approach of making chiral,
β-substituted homoallylic organoboronic esters. In the presence
of LiOtBu and a catalytic amount of silver
salt, commercial bis[(pinacolato)boryl]methane participated in the
iridium-catalyzed asymmetric allylation reactions, delivered a “CH2B(pin)” group, and yielded the title compounds from
allylic carbonates. The synthetic utility of the prepared chiral organoboronates
was demonstrated by their conversion to other important classes of
compounds.
%I ACS Publications