Asymmetric Silaboration of Terminal
Allenes Bearing α-Stereogenic Centers:
Stereoselection Based on “Reagent
Control”
Toshimichi Ohmura
Michinori Suginome
10.1021/ol060666j.s001
https://acs.figshare.com/articles/journal_contribution/Asymmetric_Silaboration_of_Terminal_Allenes_Bearing_Stereogenic_Centers_Stereoselection_Based_on_Reagent_Control_/3076906
A highly enantioface-selective silaboration of allenes having stereogenic centers at the α-positions of the double bonds has been achieved
using a combination of a chiral silylborane (−)-<b>2</b> and a chiral Pd/(<i>R</i>)-<b>3</b> catalyst. The chiral reagent system efficiently controlled the stereochemistry
of the new stereogenic centers even in the reactions of mismatched combinations.
2006-06-08 00:00:00
chiral reagent system
combination
stereogenic centers