10.1021/np060087n.s002
Zhen Xue
Zhen
Xue
Shuai Li
Shuai
Li
Sujuan Wang
Sujuan
Wang
Yinhong Wang
Yinhong
Wang
Yongchun Yang
Yongchun
Yang
Jiangong Shi
Jiangong
Shi
Lan He
Lan
He
Mono-, Bi-, and Triphenanthrenes from the Tubers of <i>Cremastra </i><i>a</i><i>ppendiculata</i>
American Chemical Society
2006
cancer cells
flavanthrinin
cell line
Triphenanthrene
biphenanthrene
monophenanthrene
trihydroxy
tubers
Cremastra appendiculataSix newphenanthrene derivatives
cirrhopetalanthin
Bi
Cremastra appendiculata
Mono
Compound
compound
Tuber
pentahydroxy
ethanolic
spectroscopic methods
dihydroxy
hydroxy
triphenanthrene
2006-06-23 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Mono_Bi_and_Triphenanthrenes_from_the_Tubers_of_i_Cremastra_i_i_a_i_i_ppendiculata_i_/3074674
Six newphenanthrene derivatives, including three monophenanthrenes (<b>1</b>−<b>3</b>), two biphenanthrenes (<b>4</b> and <b>5</b>), and a
triphenanthrene (<b>6</b>), have been isolated from an ethanolic extract of the tubers of <i>Cremastra </i><i>appendiculata</i>. Using
spectroscopic methods, the structures of compounds <b>1</b>−<b>6</b> were determined as 1-hydroxy-4,7-dimethoxy-1-(2-oxopropyl)-1<i>H</i>-phenanthren-2-one (<b>1</b>), 1,7-dihydroxy-4-methoxy-1-(2-oxopropyl)-1<i>H</i>-phenanthren-2-one (<b>2</b>), 2-hydroxy-4,7-dimethoxyphenanthrene (<b>3</b>), 2,7,2‘-trihydroxy-4,4‘,7‘-trimethoxy-1,1‘-biphenanthrene (<b>4</b>), 2,2‘-dihydroxy-4,7,4‘,7‘-tetramethoxy-1,1‘-biphenanthrene (<b>5</b>), and 2,7,2‘,7‘,2‘ ‘-pentahydroxy-4,4‘,4‘ ‘,7‘ ‘-tetramethoxy-1,8,1‘,1‘ ‘-triphenanthrene
(<b>6</b>), respectively. Compounds <b>1</b>−<b>6</b> and two known compounds, cirrhopetalanthin (<b>7</b>) and flavanthrinin (<b>8</b>), obtained
previously from this plant, were evaluated against six human cancer cells and a normal cell line.