<i>N</i>-H Carbazole Synthesis from 2-Chloroanilines via Consecutive
Amination and C−H Activation
Robin B. Bedford
Michael Betham
10.1021/jo061749g.s001
https://acs.figshare.com/articles/journal_contribution/_i_N_i_H_Carbazole_Synthesis_from_2_Chloroanilines_via_Consecutive_Amination_and_C_H_Activation/3042769
<i>N</i>-H carbazoles can be produced from 2-chloroanilines and aryl bromides via consecutive catalytic
amination and C−H activation. In many instances, this can be done in a tandem manner in one pot. The
methodologies developed can be used in the synthesis of a range of carbazoles, including the natural
products Clausine P and glycozolidine and a precursor in the synthesis of Clausines H, K, O, and
7-methoxy-<i>O</i>-methylmukonal, and can be extended to the synthesis of indoles.
2006-12-08 00:00:00
Consecutive Amination
products Clausine P
carbazole
tandem manner
Clausines H
aryl bromides
synthesis