Preparation of 2-Trialkylsiloxy-
Substituted 1,3-Dienes and Their
Diels−Alder/Cross-Coupling Reactions
Ramakrishna R. Pidaparthi
Mark E. Welker
Cynthia S. Day
Marcus W. Wright
10.1021/ol070089e.s003
https://acs.figshare.com/articles/journal_contribution/Preparation_of_2_Trialkylsiloxy_Substituted_1_3_Dienes_and_Their_Diels_Alder_Cross_Coupling_Reactions/3010996
2-Triethylsiloxy-substituted 1,3-butadiene has been prepared in gram quantities from chloroprene via a simple synthetic procedure. Silatrane
and catechol-substituted analogues of this main group element substituted diene were prepared by ligand exchange and characterized by
X-ray crystallography in addition to standard spectroscopic techniques. Diels−Alder reactions of these dienes are reported as well as subsequent
TBAF assisted/Pd-catalyzed Hiyama cross-coupling reactions of those Diels−Alder adducts.
2007-04-26 00:00:00
gram quantities
diene
Diel
spectroscopic techniques
group element
TBAF
ligand exchange