Preparation of 2-Trialkylsiloxy- Substituted 1,3-Dienes and Their Diels−Alder/Cross-Coupling Reactions Ramakrishna R. Pidaparthi Mark E. Welker Cynthia S. Day Marcus W. Wright 10.1021/ol070089e.s003 https://acs.figshare.com/articles/journal_contribution/Preparation_of_2_Trialkylsiloxy_Substituted_1_3_Dienes_and_Their_Diels_Alder_Cross_Coupling_Reactions/3010996 2-Triethylsiloxy-substituted 1,3-butadiene has been prepared in gram quantities from chloroprene via a simple synthetic procedure. Silatrane and catechol-substituted analogues of this main group element substituted diene were prepared by ligand exchange and characterized by X-ray crystallography in addition to standard spectroscopic techniques. Diels−Alder reactions of these dienes are reported as well as subsequent TBAF assisted/Pd-catalyzed Hiyama cross-coupling reactions of those Diels−Alder adducts. 2007-04-26 00:00:00 gram quantities diene Diel spectroscopic techniques group element TBAF ligand exchange