Asymmetric Synthesis of
<i>syn</i>-α-Substituted β-Amino Ketones by
Using Sulfinimines and Prochiral
Weinreb Amide Enolates
Franklin A. Davis
Minsoo Song
10.1021/ol0708166.s001
https://acs.figshare.com/articles/journal_contribution/Asymmetric_Synthesis_of_i_syn_i_Substituted_Amino_Ketones_by_Using_Sulfinimines_and_Prochiral_Weinreb_Amide_Enolates/3003256
<i>syn</i>-α-Substituted β-amino Weinreb amides are new chiral building blocks for asymmetric synthesis of <i>syn</i>-α-substituted β-amino acids,
aldehydes, and ketones and are prepared by addition of prochiral lithium enolates of Weinreb amides to sulfinimines (<i>N</i>-sulfinyl imines).
2007-06-07 00:00:00
chiral building blocks
Weinreb amides
prochiral lithium enolates
syn