10.1021/ol070889p.s001 Yanxing Jia Yanxing Jia Michèle Bois-Choussy Michèle Bois-Choussy Jieping Zhu Jieping Zhu Synthesis of DEFG Ring of Complestatin and Chloropeptin I:  Highly Atropdiastereoselective Macrocyclization by Intramolecular Suzuki-Miyaura Reaction American Chemical Society 2007 stereospecific rearrangement Atropdiastereoselective Macrocyclization DEFG ring 4 DEFG Ring 3 triggers Acidic treatment 2007-06-07 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Synthesis_of_DEFG_Ring_of_Complestatin_and_Chloropeptin_I_Highly_Atropdiastereoselective_Macrocyclization_by_Intramolecular_Suzuki_Miyaura_Reaction/3003244 Palladium-catalyzed intramolecular Suzuki-Miyaura reaction of linear tripeptide (<b>23</b>) afforded the 16-membered DEFG ring of complestatin (<b>3</b>) in good yield with an excellent atropdiastereoselectivity. Acidic treatment of <b>3</b> triggers a stereospecific rearrangement leading to the corresponding DEFG ring <b>4</b> of chloropeptin I.