2,7-Bis(1H-pyrrol-2-yl)ethynyl-1,8naphthyridine: An Ultrasensitive Fluorescent Probe for Glucopyranoside
2002-08-13T00:00:00Z (GMT) by
A push−pull conjugated molecule, 2,7-bis(1H-pyrrol-2-yl)ethynyl-1,8-naphthyridine (BPN), has been designed to bind selectively with octyl glucopyranoside (OGU). The BPN/OGU quadruple hydrogen-bonding complex adopts a rigid BPN conformation in which the proton donor (d) and acceptor (a) relays (daad) are resonantly conjugated through the ethynyl bridge, inducing π-electron delocalization, i.e., a charge transfer effect. The excellent photophysical properties make BPN a highly sensitive probe for monitoring glucopyranoside to a detection limit of ∼100 pM.