An Improved Procedure for Preparation of Carbapenem Antibiotic:  Meropenem TewariNeera NizarHashim RaiBishwa Prakash SinghShailendra K. GeorgeVinod PrasadMohan 2007 An efficient synthesis of a 1β-methyl carbapenem antibiotic, meropenem, is described. The present process does not involve cryogenic temperatures, chromatographic purification, or reverse osmosis and is amenable to large scale synthesis.