10.1021/jo071029p.s002
Satoshi Inoue
Satoshi
Inoue
Yoshiya Fukumoto
Yoshiya
Fukumoto
Naoto Chatani
Naoto
Chatani
A Chelation-Assisted Transformation: Synthesis
of Maleimides by the Rh-Catalyzed
Carbonylation of Alkynes with
Pyridin-2-ylmethylamine
American Chemical Society
2007
Carbonylation
presence
rhodium center
maleimide derivatives 3.
Transformation
pyridine nitrogen
Rh
coordination
Pyridin
Synthesi
CO
molecule
Alkyne
Maleimide
incorporation
alkynes 1
2007-08-17 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/A_Chelation_Assisted_Transformation_Synthesis_of_Maleimides_by_the_Rh_Catalyzed_Carbonylation_of_Alkynes_with_Pyridin_2_ylmethylamine/2990608
The reaction of alkynes <b>1</b> with CO and pyridin-2-ylmethylamine (<b>2</b>) in the presence of Rh<sub>4</sub>(CO)<sub>12</sub>/P(OEt)<sub>3</sub> results in
the incorporation of two molecules of CO leading to
maleimide derivatives <b>3</b>. The coordination of the pyridine
nitrogen in <b>2</b> to a rhodium center is essential for the reaction
to proceed.