10.1021/jo071029p.s002 Satoshi Inoue Satoshi Inoue Yoshiya Fukumoto Yoshiya Fukumoto Naoto Chatani Naoto Chatani A Chelation-Assisted Transformation:  Synthesis of Maleimides by the Rh-Catalyzed Carbonylation of Alkynes with Pyridin-2-ylmethylamine American Chemical Society 2007 Carbonylation presence rhodium center maleimide derivatives 3. Transformation pyridine nitrogen Rh coordination Pyridin Synthesi CO molecule Alkyne Maleimide incorporation alkynes 1 2007-08-17 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/A_Chelation_Assisted_Transformation_Synthesis_of_Maleimides_by_the_Rh_Catalyzed_Carbonylation_of_Alkynes_with_Pyridin_2_ylmethylamine/2990608 The reaction of alkynes <b>1</b> with CO and pyridin-2-ylmethylamine (<b>2</b>) in the presence of Rh<sub>4</sub>(CO)<sub>12</sub>/P(OEt)<sub>3</sub> results in the incorporation of two molecules of CO leading to maleimide derivatives <b>3</b>. The coordination of the pyridine nitrogen in <b>2</b> to a rhodium center is essential for the reaction to proceed.