Dehydrogenation of Inert Alkyl Groups via Remote C−H Activation: Converting a Propyl Group into a π-Allylic Complex
Ramesh Giri
Nathan Maugel
Bruce M. Foxman
Jin-Quan Yu
10.1021/om8000444.s004
https://acs.figshare.com/articles/dataset/Dehydrogenation_of_Inert_Alkyl_Groups_via_Remote_C_H_Activation_Converting_a_Propyl_Group_into_a_Allylic_Complex/2942614
Pd(OAc)<sub>2</sub>-mediated dehydrogenation of an alkyl group to a double bond or a η<sup>3</sup>-allylic complex via sp<sup>3</sup> C−H bond activation and allylic oxidation is reported. A novel redox is proposed for this double oxidation under oxidant-free conditions. A catalytic protocol using benzoquinone as the stoichiometric oxidant has also been developed for the dehydrogenation of cyclopentylcarboxamides.
2008-04-28 00:00:00
Allylic
Inert Alkyl Groups
dehydrogenation
benzoquinone
stoichiometric oxidant
ComplexPd
Activation
alkyl group
Remote
activation
Propyl Group
allylic oxidation
cyclopentylcarboxamide
novel redox
sp
Dehydrogenation
Converting
bond