%0 Journal Article %A Kang, Qiang %A Zhao, Zhuo-An %A You, Shu-Li %D 2008 %T Asymmetric Transfer Hydrogenation of β,γ-Alkynyl α-Imino Esters by a Brønsted Acid %U https://acs.figshare.com/articles/journal_contribution/Asymmetric_Transfer_Hydrogenation_of_Alkynyl_Imino_Esters_by_a_Br_nsted_Acid/2939113 %R 10.1021/ol800494r.s001 %2 https://acs.figshare.com/ndownloader/files/4637800 %K Br ønsted %K imino %K alkynyl %K Utilizing Hantzsch esters %K chiral phosphoric acid %K Asymmetric Transfer Hydrogenation %K imine moieties %K Asymmetric synthesis %K transfer hydrogenation %K hydrogen donor %X Asymmetric synthesis of trans-alkenyl α-amino esters was realized by chiral phosphoric acid catalyzed transfer hydrogenation of β,γ-alkynyl α-imino esters. Utilizing Hantzsch esters as the hydrogen donor, both the alkyne and imine moieties of β,γ-alkynyl α-imino esters were reduced to afford trans-alkenyl α-amino esters with up to 96% ee. %I ACS Publications