Lipshutz, Bruce H. Chung, David W. Rich, Brian Sonogashira Couplings of Aryl Bromides: Room Temperature, Water Only, No Copper Cross-coupling reactions between lipophilic terminal alkynes and aryl bromides can be catalyzed by ligated Pd, in the absence of copper, in pure water at ambient temperatures. Small amounts of the nonionic amphiphile PTS assist by virtue of nanometer micelles formed spontaneously in an aqueous medium. Aryl Bromides;amphiphile PTS;lipophilic terminal alkynes;absence;ligated Pd;nanometer micelles;Sonogashira Couplings;ambient temperatures;medium;Small amounts;virtue;aryl bromides;Room Temperature 2008-09-04
    https://acs.figshare.com/articles/journal_contribution/Sonogashira_Couplings_of_Aryl_Bromides_Room_Temperature_Water_Only_No_Copper/2916646
10.1021/ol801471f.s001