10.1021/ol8013864.s001
Andrew G. H. Wee
Andrew
G. H. Wee
Gao-Jun Fan
Gao-Jun
Fan
Asymmetric Synthesis of (+)-Isofebrifugine and (−)-Sedacryptine from a Common Chiral Nonracemic Building Block
American Chemical Society
2008
Sedacryptine
alkaloids
isofebrifugine
flexibilty
functionalized nonracemic bicyclic building block
sedacryptine
approach
Asymmetric Synthesis
stereoselective syntheses
Isofebrifugine
disubstituted
hydroxypiperidine
Common Chiral Nonracemic Building Block
2008-09-04 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Asymmetric_Synthesis_of_Isofebrifugine_and_Sedacryptine_from_a_Common_Chiral_Nonracemic_Building_Block/2916559
The stereoselective syntheses of 2-substituted and 2,6-disubstituted 3-hydroxypiperidine alkaloids, (+)-isofebrifugine and (−)-sedacryptine, from a common, functionalized nonracemic bicyclic building block are achieved, demonstrating the flexibilty of the approach.