%0 Journal Article
%A Amat, Mercedes
%A PeĢrez, Maria
%A Minaglia, Annamaria T.
%A Bosch, Joan
%D 2008
%T An Enantioselective Synthetic Route to cis-2,4-Disubstituted and 2,4-Bridged Piperidines
%U https://acs.figshare.com/articles/journal_contribution/An_Enantioselective_Synthetic_Route_to_i_cis_i_2_4_Disubstituted_and_2_4_Bridged_Piperidines/2915833
%R 10.1021/jo801172b.s001
%2 https://acs.figshare.com/ndownloader/files/4614145
%K Enantioselective
%K Piperidine
%K ci
%K Bridged
%K piperidine
%K stereoselective conjugate addition
%K bridged
%K substituent
%K lactam
%K organocuprate
%K enantiopure
%X A synthetic route to enantiopure cis-2,4-disubstituted and 2,4-bridged piperidines is reported, the key step being a stereoselective conjugate addition of an organocuprate to a phenylglycinol-derived unsaturated lactam bearing a substituent at the 8a-position.
%I ACS Publications