%0 Journal Article %A Amat, Mercedes %A PeĢrez, Maria %A Minaglia, Annamaria T. %A Bosch, Joan %D 2008 %T An Enantioselective Synthetic Route to cis-2,4-Disubstituted and 2,4-Bridged Piperidines %U https://acs.figshare.com/articles/journal_contribution/An_Enantioselective_Synthetic_Route_to_i_cis_i_2_4_Disubstituted_and_2_4_Bridged_Piperidines/2915833 %R 10.1021/jo801172b.s001 %2 https://acs.figshare.com/ndownloader/files/4614145 %K Enantioselective %K Piperidine %K ci %K Bridged %K piperidine %K stereoselective conjugate addition %K bridged %K substituent %K lactam %K organocuprate %K enantiopure %X A synthetic route to enantiopure cis-2,4-disubstituted and 2,4-bridged piperidines is reported, the key step being a stereoselective conjugate addition of an organocuprate to a phenylglycinol-derived unsaturated lactam bearing a substituent at the 8a-position. %I ACS Publications