%0 Journal Article %A Hatano, Bunpei %A Nagahashi, Keita %A Kijima, Tatsuro %D 2008 %T Zinc-Mediated Allylation and Alkylation of Aminals in the Presence of TMSCl and Diisopropylamine %U https://acs.figshare.com/articles/journal_contribution/Zinc_Mediated_Allylation_and_Alkylation_of_Aminals_in_the_Presence_of_TMSCl_and_Diisopropylamine/2898391 %R 10.1021/jo8019797.s001 %2 https://acs.figshare.com/ndownloader/files/4596532 %K diisopropylamine %K bromoacetate %K presence %K Alkylation %K bromonitrile %K Aminal %K Allylation %K alkylation %K reaction system %K Diisopropylamine %K allyl bromide %K benzyl bromide %K aminal %K TMSCl %K Presence %K butaverine %K organozinc reagents %K synthesis %K antispasmodic %X An alkylation of aminals with organozinc reagents derived from allyl bromide, benzyl bromide, α-bromoacetate, and α-bromonitrile proceeded efficiently in the presence of TMSCl and diisopropylamine. This reaction system was applied to the synthesis of an antispasmodic: butaverine. %I ACS Publications