10.1021/jo801831c.s001 Dahong Jiang Dahong Jiang Yuanwei Chen Yuanwei Chen Reduction of Δ<sup>2</sup>-Isoxazolines to β-Hydroxy Ketones with Iron and Ammonium Chloride as Reducing Agent American Chemical Society 2008 Ammonium Chloride water results ammonium chloride chemoselective protocol ketone hydroxy 2008-11-21 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Reduction_of_sup_2_sup_Isoxazolines_to_Hydroxy_Ketones_with_Iron_and_Ammonium_Chloride_as_Reducing_Agent/2898349 A detailed study of a procedure for the selective reduction of Δ<sup>2</sup>-isoxazolines to the corresponding β-hydroxy ketones is reported. The use of iron and ammonium chloride as the reducing agent in the presence of water results in a facile and chemoselective protocol for the preparation of β-hydroxy ketones, including the conjugated β-hydroxy ketones.