10.1021/ol802745n.s001 M. Daniel Spantulescu M. Daniel Spantulescu Marc A. Boudreau Marc A. Boudreau John C. Vederas John C. Vederas Retention of Configuration in Photolytic Decarboxylation of Peresters to Form Chiral Acetals and Ethers American Chemical Society 2009 malic acids site decarboxylation ether retention Chiral acyclic acetals absence wavelength UV light Configuration tartaric Photolytic Decarboxylation stereochemical control temperature results configuration carbonyl photolyzed Ethers Peresters precursor yield process proceeds Form Chiral Acetals 2009-02-05 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Retention_of_Configuration_in_Photolytic_Decarboxylation_of_Peresters_to_Form_Chiral_Acetals_and_Ethers/2880871 Peresters generate ethers in good yields when photolyzed in the absence of solvent using short wavelength UV light. At −78 °C or below, the process proceeds predominantly with retention of configuration at the site adjacent to the carbonyl where the decarboxylation occurs, but increase in temperature results in loss of stereochemical control. Chiral acyclic acetals can be prepared using precursors derived from tartaric or malic acids.