10.1021/ol802613r.s001 Nicole Seah Nicole Seah Paul V. Santacroce Paul V. Santacroce Amit Basu Amit Basu Probing the Lactose·GM3 Carbohydrate−Carbohydrate Interaction with Glycodendrimers American Chemical Society 2009 presence generation Glycodendrimers Multivalent glycoconjugates Lactose Langmuir monolayers Interaction GM 3 Excessive carbohydrate valency PAMAM interaction GM 3 monolayer calcium ions Carbohydrate 2009-02-05 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Probing_the_Lactose_GM3_Carbohydrate_Carbohydrate_Interaction_with_Glycodendrimers/2880760 Multivalent glycoconjugates were prepared using generation-4 PAMAM dendrimers, and their interaction with Langmuir monolayers containing GM3 was investigated. Excessive carbohydrate valency adversely affects the carbohydrate−carbohydrate interaction. The GM3 monolayer selectively interacts with lactose-functionalized dendrimers in the presence of calcium ions.