10.1021/np900029z.s001 Li-She Gan Li-She Gan Gang Ren Gang Ren Jian-Xia Mo Jian-Xia Mo Xiang-Yi Zhang Xiang-Yi Zhang Wei Yao Wei Yao Chang-Xin Zhou Chang-Xin Zhou Cycloartane Triterpenoids from <i>Kleinhovia hospita</i> American Chemical Society 2009 gardenolic acid B Hep Cycloartane Triterpenoids diacetal compound 4 IR Kleinhovia hospita cycloartane triterpenoids configuration cytotoxicity spectroscopic methods Kleinhovia hospitaFour hepatoprotective effects 2 D NMR ketone moieties 2009-06-26 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Cycloartane_Triterpenoids_from_i_Kleinhovia_hospita_i_/2847457 Four new cycloartane triterpenoids, together with the known gardenolic acid B, were isolated from <i>Kleinhovia hospita</i>. The triterpenoids (<b>1</b>−<b>3</b>) contain a unique 21,23-diacetal side-chain, while compound <b>4</b> contains two α,β-unsaturated ketone moieties. Their structures and relative configurations were determined by spectroscopic methods, including 2D NMR and IR. These compounds showed promising hepatoprotective effects on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells.