10.1021/om9004884.s001 Min-Soo Jang Min-Soo Jang Xi Wang Xi Wang Woo-Young Jang Woo-Young Jang Hye-Young Jang Hye-Young Jang Pt(II)/SnX<sub>2</sub> (X = Cl, Br)-Catalyzed Cyclization: Completely Different Reactivity of the Platinum Complex toward 1,6-Haloenynes and 1,6-Enynes American Chemical Society 2009 reaction conditions reaction mechanisms control experiments Pt catalyst enyne halogen substituent cycloisomerization halide substituent Platinum Complex reaction routes substrate scope haloenyne Pt catalyst conditions 2009-08-24 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Pt_II_SnX_sub_2_sub_X_Cl_Br_Catalyzed_Cyclization_Completely_Different_Reactivity_of_the_Platinum_Complex_toward_1_6_Haloenynes_and_1_6_Enynes/2833378 Using a Pt catalyst generated from PtX<sub>2</sub>, SnX<sub>2</sub>, phosphines, and H<sub>2</sub>, the cyclizations of haloenynes and enynes without a halide substituent were investigated. Under the Pt catalyst conditions, the reaction routes were partitioned into the cycloisomerization of the haloenynes and the cycloreduction of the enynes without a halogen substituent. Through the optimization of the reaction conditions and control experiments, we proposed plausible catalytic cycles to account for the bifurcation of the reaction mechanisms in addition to the demonstration of the substrate scope of the cycloisomerization of the haloenynes.