10.1021/om9004884.s001
Min-Soo Jang
Min-Soo
Jang
Xi Wang
Xi
Wang
Woo-Young Jang
Woo-Young
Jang
Hye-Young Jang
Hye-Young
Jang
Pt(II)/SnX<sub>2</sub> (X = Cl, Br)-Catalyzed Cyclization: Completely Different Reactivity of the Platinum Complex toward 1,6-Haloenynes and 1,6-Enynes
American Chemical Society
2009
reaction conditions
reaction mechanisms
control experiments
Pt catalyst
enyne
halogen substituent
cycloisomerization
halide substituent
Platinum Complex
reaction routes
substrate scope
haloenyne
Pt catalyst conditions
2009-08-24 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Pt_II_SnX_sub_2_sub_X_Cl_Br_Catalyzed_Cyclization_Completely_Different_Reactivity_of_the_Platinum_Complex_toward_1_6_Haloenynes_and_1_6_Enynes/2833378
Using a Pt catalyst generated from PtX<sub>2</sub>, SnX<sub>2</sub>, phosphines, and H<sub>2</sub>, the cyclizations of haloenynes and enynes without a halide substituent were investigated. Under the Pt catalyst conditions, the reaction routes were partitioned into the cycloisomerization of the haloenynes and the cycloreduction of the enynes without a halogen substituent. Through the optimization of the reaction conditions and control experiments, we proposed plausible catalytic cycles to account for the bifurcation of the reaction mechanisms in addition to the demonstration of the substrate scope of the cycloisomerization of the haloenynes.