Shibata, Takanori Uchiyama, Toshifumi Endo, Kohei Enantioselective Synthesis of Chiral Tripodal Cage Compounds by [2 + 2 + 2] Cycloaddition of Branched Triynes Cyclotrimerization of triynes branched by a nitrogen atom of 2-aminophenol yielded planar-chiral tripodal cage compounds. When a cationic Rh−Me-DUPHOS catalyst was used, the cycloadducts were obtained in high yield and excellent ee, and a macrocyclic compound with a [15]cyclophane system was also obtained. This method can be further applied to the synthesis of a triarmed pyridinophane by the intramolecular reaction of a diyne−nitrile. tripodal;aminophenol;macrocyclic compound;Rh;Branched Triynes Cyclotrimerization;cycloadduct;cationic;ee;method;cyclophane;diyne;intramolecular reaction;nitrogen atom;catalyst;cage;Chiral Tripodal Cage Compounds;triarmed pyridinophane;triyne;Enantioselective Synthesis;synthesis;Cycloaddition 2009-09-03
    https://acs.figshare.com/articles/dataset/Enantioselective_Synthesis_of_Chiral_Tripodal_Cage_Compounds_by_2_2_2_Cycloaddition_of_Branched_Triynes/2830792
10.1021/ol9014893.s002