%0 Generic %A Shibata, Takanori %A Uchiyama, Toshifumi %A Endo, Kohei %D 2009 %T Enantioselective Synthesis of Chiral Tripodal Cage Compounds by [2 + 2 + 2] Cycloaddition of Branched Triynes %U https://acs.figshare.com/articles/dataset/Enantioselective_Synthesis_of_Chiral_Tripodal_Cage_Compounds_by_2_2_2_Cycloaddition_of_Branched_Triynes/2830792 %R 10.1021/ol9014893.s002 %2 https://acs.figshare.com/ndownloader/files/4528492 %K tripodal %K aminophenol %K macrocyclic compound %K Rh %K Branched Triynes Cyclotrimerization %K cycloadduct %K cationic %K ee %K method %K cyclophane %K diyne %K intramolecular reaction %K nitrogen atom %K catalyst %K cage %K Chiral Tripodal Cage Compounds %K triarmed pyridinophane %K triyne %K Enantioselective Synthesis %K synthesis %K Cycloaddition %X Cyclotrimerization of triynes branched by a nitrogen atom of 2-aminophenol yielded planar-chiral tripodal cage compounds. When a cationic Rh−Me-DUPHOS catalyst was used, the cycloadducts were obtained in high yield and excellent ee, and a macrocyclic compound with a [15]cyclophane system was also obtained. This method can be further applied to the synthesis of a triarmed pyridinophane by the intramolecular reaction of a diyne−nitrile. %I ACS Publications