%0 Journal Article %A Takamura, Hiroyoshi %A Murata, Takeshi %A Asai, Takahiro %A Kadota, Isao %A Uemura, Daisuke %D 2009 %T Stereoselective Synthesis and Absolute Configuration of the C1′−C25′ Fragment of Symbiodinolide %U https://acs.figshare.com/articles/journal_contribution/Stereoselective_Synthesis_and_Absolute_Configuration_of_the_C1_C25_Fragment_of_Symbiodinolide/2830240 %R 10.1021/jo901162v.s001 %2 https://acs.figshare.com/ndownloader/files/4527940 %K SymbiodinolideStereoselective synthesis %K Stereoselective Synthesis %K symbiodinolide %K olefination %K Fragment %K enantio %K side chains %K route features Kotsuki %K fragment %K stereoselective synthesis %K configuration %K Julia %K hydrolysis %K introduction %K Absolute Configuration %X Stereoselective synthesis of the C1′−C25′ fragment of symbiodinolide, which was obtained as a degraded product from symbiodinolide by alkaline hydrolysis, has been accomplished. The synthetic route features Kotsuki coupling and Julia−Kocienski olefination in the introduction of the side chains. This enantio- and stereoselective synthesis has established the absolute configuration of the C1′−C25′ fragment. %I ACS Publications