Crossed Intramolecular Rauhut−Currier-Type Reactions via Dienamine Activation
Eugenia Marqués-López
Raquel P. Herrera
Timo Marks
Wiebke C. Jacobs
Daniel Könning
Renata M. de Figueiredo
Mathias Christmann
10.1021/ol901614t.s002
https://acs.figshare.com/articles/dataset/Crossed_Intramolecular_Rauhut_Currier_Type_Reactions_via_Dienamine_Activation/2827564
The intramolecular Rauhut−Currier reaction creates a carbon−carbon bond between two tethered Michael acceptors. Previous asymmetric versions have relied on 1,4-additions of chiral nucleophilic catalysts. Herein, we investigate a novel strategy that involves the formation of electron rich dienamines as key intermediates. Our methodology provides an efficient entry to the iridoid framework.
2009-09-17 00:00:00
dienamine
chiral nucleophilic catalysts
intramolecular
novel strategy
iridoid framework
Rauhut
methodology
version
Dienamine Activation
intermediate
electron
Crossed
entry
Michael acceptors
Herein
Intramolecular
formation
Previous
bond