Synthetic Study on Tetrapetalones: Stereoselective Cyclization of <i>N</i>-Acyliminium Ion To Construct Substituted 1-Benzazepines Cheng Li Xinyu Li Ran Hong 10.1021/ol901349b.s002 https://acs.figshare.com/articles/dataset/Synthetic_Study_on_Tetrapetalones_Stereoselective_Cyclization_of_i_N_i_Acyliminium_Ion_To_Construct_Substituted_1_Benzazepines/2827426 The synthesis of the tetracyclic core of complex antibiotic tetrapetalones has been achieved in three steps starting from the simple intermediate γ-hydroxy amide, which can be accessed through a high-yielding six-step sequence. The successful synthesis relies on a novel strategy based on the <i>N</i>-acyliminium ion cyclization. 2009-09-17 00:00:00 tetracyclic core sequence novel strategy Synthetic Study antibiotic tetrapetalones cyclization Ion Substituted Stereoselective Cyclization synthesis Benzazepine Tetrapetalone amide hydroxy