10.1021/am900526u.s001
Guo-Dong Fu
Guo-Dong
Fu
Li-Qun Xu
Li-Qun
Xu
Fang Yao
Fang
Yao
Guo-Liang Li
Guo-Liang
Li
En-Tang Kang
En-Tang
Kang
Smart Nanofibers with a Photoresponsive Surface for Controlled Release
American Chemical Society
2009
prodrug
Photoresponsive Surface
nanofiber
Smart Nanofibers
host
interaction
surface modification
block copolymer
2009-11-25 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Smart_Nanofibers_with_a_Photoresponsive_Surface_for_Controlled_Release/2810380
A novel photocontrolled “ON−OFF” release system for the α-cyclodextrin-5-fluorouracial (α-CD−5FU) prodrug, based on host−guest interaction on the photoresponsive and cross-linked nanofiber surface, was demonstrated. The nanofibers with a stimuli-responsive surface were electrospun from the block copolymer prepared via controlled radical polymerization, followed by surface modification via “Click Chemistry”, and loading of the prodrug via host−guest interaction.