Ma, Hai Liu, Kun Zhang, Fa-Guang Zhu, Chuan-Le Nie, Jing Ma, Jun-An Chiral Bifunctional Thiourea-Catalyzed Enantioselective Michael Addition of Ketones to Nitrodienes Simple bifunctional thioureas, derived from the commercially available saccharides and chiral diamines, have been shown tunably to promote Michael-type addition of ketones to α,β−γ,δ-nitrodienes. The Michael adducts were obtained in good yields albeit with high enantioselectivites (84−99% ee). Furthermore, these products can be readily transformed into more useful molecules. Enantioselective;Michael adducts;enantioselectivite;ketone;chiral diamines;ee;saccharide;NitrodienesSimple bifunctional thioureas;nitrodiene;Bifunctional;Chiral;molecule;Ketone;yield;tunably 2010-03-05
    https://acs.figshare.com/articles/journal_contribution/Chiral_Bifunctional_Thiourea_Catalyzed_Enantioselective_Michael_Addition_of_Ketones_to_Nitrodienes/2786401
10.1021/jo901991v.s004