Gukulenins A and B, Cytotoxic Tetraterpenoids from the Marine Sponge <i>Phorbas gukulensis</i>
Su Young Park
Hyukjae Choi
Hoosang Hwang
Heonjoong Kang
Jung-Rae Rho
10.1021/np900606h.s001
https://acs.figshare.com/articles/journal_contribution/Gukulenins_A_and_B_Cytotoxic_Tetraterpenoids_from_the_Marine_Sponge_i_Phorbas_gukulensis_i_/2774848
Gukulenins A (<b>1</b>) and B (<b>2</b>), both having an unprecedented skeleton with a bis-tropolone moiety, were isolated from the Korean marine sponge <i>Phorbas gukulensis</i>. They exhibited significant cytotoxicity against human pharynx, stomach, colon, and renal cancer cell lines in the range 0.05−0.80 μM.
2010-04-23 00:00:00
cancer cell lines
skeleton
moiety
Cytotoxic Tetraterpenoids
Marine Sponge Phorbas gukulensisGukulenins
pharynx
cytotoxicity
Korean marine sponge Phorbas gukulensis