%0 Journal Article %A Liu, Zhen %A Shi, Min %D 2010 %T Catalytic Enantioselective Addition of Cyclic β-Keto Esters with Activated Olefins and N-Boc Imines Using Chiral C2-Symmetric Cationic Pd2+ N-Heterocyclic Carbene (NHC) Diaqua Complexes %U https://acs.figshare.com/articles/journal_contribution/Catalytic_Enantioselective_Addition_of_Cyclic_Keto_Esters_with_Activated_Olefins_and_N_Boc_Imines_Using_Chiral_i_C_i_sub_2_sub_Symmetric_Cationic_Pd_sup_2_sup_N_Heterocyclic_Carbene_NHC_Diaqua_Complexes/2757937 %R 10.1021/om100331z.s002 %2 https://acs.figshare.com/ndownloader/files/4450735 %K Pd %K Activated Olefins %K NHC %K Catalytic Enantioselective Addition %K diaqua %K Diaqua ComplexesThe %K catalyst %X The asymmetric addition of cyclic β-keto esters to activated olefins and N-Boc imines was realized by using chiral cationic C2-symmetric N-heterocyclic carbene (NHC) Pd2+ diaqua complexes 1a,b as the catalysts, producing the corresponding adducts in moderate to high yields (up to 95%) and with good to high enantioselectivities (up to 96% ee). Nevertheless, the most significant observation is that when the (R)-NHC Pd2+ diaqua complex was used in these reactions, different absolute configurations were observed in comparison to those obtained with catalysts obtained from (R)-phosphane ligands. %I ACS Publications