%0 Generic %A Yang, Hua %A Carter, Rich G. %D 2010 %T Synthesis of All-Carbon, Quaternary Center-Containing Cyclohexenones through an Organocatalyzed, Multicomponent Coupling %U https://acs.figshare.com/articles/dataset/Synthesis_of_All_Carbon_Quaternary_Center_Containing_Cyclohexenones_through_an_Organocatalyzed_Multicomponent_Coupling/2756356 %R 10.1021/ol1011955.s004 %2 https://acs.figshare.com/ndownloader/files/4448848 %K enamine %K diastereoselectivity %K functionalized cyclohexenones %K accessing %K Cyclohexenone %K quaternary center %K enantio %K enantioselectivity %K contrast %K Synthesi %K Organocatalyzed multicomponent %K Quaternary %K sieve %K proline aryl sulfonamide %K Multicomponent %X Organocatalyzed multicomponent coupling using a new ester-containing, proline aryl sulfonamide has been developed for accessing densely functionalized cyclohexenones, each containing a quaternary center in high enantio- and diastereoselectivity. In contrast to most enamine/iminium-catalyzed reactions, the use of molecular sieves was critical to optimum enantioselectivity. %I ACS Publications