Diastereoselective Syntheses of Functionalized Five-Membered Carbocycles and Heterocycles by a SmI<sub>2</sub>-Promoted Intramolecular Coupling of Bromoalkynes and α,β-Unsaturated Esters
Kazunori Takahashi
Toshio Honda
10.1021/ol101034s.s002
https://acs.figshare.com/articles/journal_contribution/Diastereoselective_Syntheses_of_Functionalized_Five_Membered_Carbocycles_and_Heterocycles_by_a_SmI_sub_2_sub_Promoted_Intramolecular_Coupling_of_Bromoalkynes_and_Unsaturated_Esters/2756254
An intramolecular coupling of bromoalkynes with α,β-unsaturated esters afforded functionalized five-membered carbocycles and heterocycles with high diastereoselectivities in excellent yields. The vinyl bromides newly generated as the products serve as adequate intermediates for further chemical modification.
2010-07-02 00:00:00
esters
functionalized
bromoalkyne
intramolecular
yield
Ester
Carbocycle
Heterocycle
diastereoselectivitie
chemical modification
vinyl bromides
SmI
carbocycle
heterocycle
intermediate
Functionalized
Diastereoselective Syntheses
Bromoalkyne
Intramolecular
Unsaturated