Immunoproteomic Approach to Elucidating the Pathogenesis of Cryptococcosis Caused by <i>Cryptococcus gattii</i>
Sarah E. Jobbins
Cameron J. Hill
Jocelyn M. D’Souza-Basseal
Matthew P. Padula
Ben R. Herbert
Mark B. Krockenberger
10.1021/pr100028t.s003
https://acs.figshare.com/articles/journal_contribution/Immunoproteomic_Approach_to_Elucidating_the_Pathogenesis_of_Cryptococcosis_Caused_by_i_Cryptococcus_gattii_i_/2745487
Cryptococcosis caused by <i>Cryptococcus gattii</i> is a devastating disease of immunocompetent hosts with an incompletely understood pathogenesis. Utilizing an immunoproteomic approach in a naturally occurring koala model of disease, a number of key proteins and pathways are identified in the early and late pathogenesis of cryptococcosis for the first time. In particular, the thioredoxin system appears important in the pathogenesis of cryptococcosis caused by <i>C. gattii</i> VGII.
2010-08-06 00:00:00
Cryptococcus gattiiCryptococcosis
thioredoxin system
pathogenesis
koala model
immunocompetent hosts
cryptococcosi
gattii VGII
Immunoproteomic Approach
Cryptococcus gattii
immunoproteomic approach