Pitucamycin: Structural Merger of a Phenoxazinone with an Epoxyquinone Antibiotic
Patrícia Bezerra Gomes
Markus Nett
Hans-Martin Dahse
Christian Hertweck
10.1021/np100344u.s001
https://acs.figshare.com/articles/journal_contribution/Pitucamycin_Structural_Merger_of_a_Phenoxazinone_with_an_Epoxyquinone_Antibiotic/2727493
Chemical profiling of a <i>Streptomyces griseus</i> strain isolated from an old building with moisture damage led to the discovery of two novel phenoxazinones, chandrananimycin D (<b>1</b>) and pitucamycin (<b>2</b>), along with the known grixazone B (<b>3</b>). Pitucamycin represents an unprecedented hybrid molecule composed of a phenoxazinone and an enaminomycin-like epoxyquinone moiety.
2010-09-24 00:00:00
Phenoxazinone
chandrananimycin
grixazone
Streptomyces griseus strain
moiety
Epoxyquinone AntibioticChemical
Structural Merger
epoxyquinone
molecule
Pitucamycin
pitucamycin
moisture damage
novel phenoxazinones