Marcus, Andrew P. Sarpong, Richmond Synthesis of the Tetracyclic Core of Tetrapetalone A Enabled by a Pyrrole Reductive Alkyation The tetracyclic framework of the tetrapetalone A aglycon has been secured through synthesis. A reductive pyrrole alkylation enables the formation of a key tetrasubstituted carbon stereocenter, and the tetramic acid portion of the molecule can be accessed through silicon or boronic ester conjugate addition to an ene-lactam. Pyrrole Reductive Alkyation;tetracyclic framework;reductive pyrrole alkylation;synthesis;Tetracyclic Core;molecule;Enabled;formation;Tetrapetalone;tetramic acid portion;boronic ester conjugate addition;aglycon;tetrasubstituted carbon stereocenter;silicon;tetrapetalone;Synthesi 2010-10-15
    https://acs.figshare.com/articles/journal_contribution/Synthesis_of_the_Tetracyclic_Core_of_Tetrapetalone_A_Enabled_by_a_Pyrrole_Reductive_Alkyation/2721784
10.1021/ol1018536.s001