%0 Generic
%A Tabata, Hidetsugu
%A Wada, Naoya
%A Takada, Yuko
%A Oshitari, Tetsuta
%A Takahashi, Hideyo
%A Natsugari, Hideaki
%D 2011
%T Isolation and Characterization of Atropisomers of Seven-Membered-Ring Benzolactams
%U https://acs.figshare.com/articles/dataset/Isolation_and_Characterization_of_Atropisomers_of_Seven_Membered_Ring_Benzolactams/2640985
%R 10.1021/jo2008725.s005
%2 https://acs.figshare.com/ndownloader/files/4293040
%K benzolactam
%K atropisomer
%K benzothiazepin
%K BenzolactamsThe
%K moiety
%K barrier
%K atropisomeric
%K crystallography
%K benzodiazepin
%K Isolation
%K diastereomer
%K benzazepin
%K Characterization
%K interconversion
%K Atropisomer
%X The atropisomeric properties of seven-membered-ring benzolactams (7a–c and 8a) [1,5-benzodiazepin-2-one (a), 1,5-benzothiazepin-4-one (b), and 1-benzazepin-2-one (c)] were examined. The atropisomers were isolated as the diastereomers with an (S)-phenethylamide moiety, which were characterized by X-ray crystallography, and the barriers to their interconversion were clarified.
%I ACS Publications