Collett, Nathan D. Carter, Rich G. Stereoselective Synthesis of the Eastern Quinolizidine Portion of Himeradine A The synthesis of the C<sub>15</sub>–C<sub>17</sub>/N<sub>1′</sub>–C<sub>11′</sub> quinolizidine portion of himeradine A is disclosed. An intramolecular, heteroatom Michael addition was employed to establish the C<sub>6′</sub> stereogenic center with high diastereoselectivity. The quinolizidine ring was constructed using microwave-induced cyclization at the N<sub>1′</sub>–C<sub>2′</sub> position. The C<sub>17</sub> stereogenic center was introduced through a diastereoselective Overman rearrangement. diastereoselectivity;himeradine;intramolecular;Stereoselective Synthesis;quinolizidine ring;cyclization;Himeradine AThe synthesis;diastereoselective Overman rearrangement;heteroatom Michael addition;Eastern Quinolizidine Portion;portion;C 17 stereogenic center 2011-08-05
    https://acs.figshare.com/articles/dataset/Stereoselective_Synthesis_of_the_Eastern_Quinolizidine_Portion_of_Himeradine_A/2626092
10.1021/ol201704g.s003