%0 Journal Article
%A Subramanium, Sri S.
%A Handa, Sachin
%A Miranda, Anthea J.
%A Slaughter, LeGrande M.
%D 2011
%T Simple Silver Salts and Palladium Bis(N-heterocyclic carbene) Complexes As Complementary Catalysts for the Nazarov Cyclization
%U https://acs.figshare.com/articles/journal_contribution/Simple_Silver_Salts_and_Palladium_Bis_i_N_i_heterocyclic_carbene_Complexes_As_Complementary_Catalysts_for_the_Nazarov_Cyclization/2605033
%R 10.1021/cs200449g.s001
%2 https://acs.figshare.com/ndownloader/files/4254286
%K esters
%K Nazarov CyclizationSimple silver salts
%K Nazarov cyclizations
%K palladium
%K Simple Silver Salts
%K Complementary Catalysts
%K Nazarov reactions
%K bi
%K silver salts
%K carbene
%K AgSbF 6
%K keto
%K catalyst
%X Simple silver salts and dicationic palladium bis(N-heterocyclic carbene) complexes were found to be effective and complementary catalysts for Nazarov cyclizations of divinyl β-keto esters. A sterically hindered palladium bis(NHC) catalyst provided remarkable endo:exo selectivity in cyclizations of cyclohexenyl β-keto esters, whereas AgSbF6 gave improved yields with electron-deficient substrates. The high activities observed with silver salts are significant, given their widespread use as additives in catalytic Nazarov reactions.
%I ACS Publications