10.1021/jo201879t.s001
Chun-Bao Miao
Chun-Bao
Miao
Min Zhang
Min
Zhang
Zong-Yong Tian
Zong-Yong
Tian
Hai-Tao Xi
Hai-Tao
Xi
Xiao-Qiang Sun
Xiao-Qiang
Sun
Hai-Tao Yang
Hai-Tao
Yang
Base-Controlled Selective
Conversion of Michael Adducts
of Malonates with Enones in the Presence of Iodine
American Chemical Society
2011
Conversion
iodine
O 2
presence
malonate
hydroxylmalonate
Michael adducts
IodineAn
conversion
derivative
Enone
functionalized cyclopropane
NaOAc
oxetane
formation
enone
Presence
DBU
Malonate
Michael Adducts
Na 2CO
2011-12-02 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Base_Controlled_Selective_Conversion_of_Michael_Adducts_of_Malonates_with_Enones_in_the_Presence_of_Iodine/2576014
An efficient base-controlled selective conversion of
the Michael
adducts of malonates with enones in the presence of iodine is reported.
Highly functionalized cyclopropane, oxetane, and α-hydroxylmalonate
derivatives are obtained selectively using DBU, Na<sub>2</sub>CO<sub>3</sub>, and NaOAc as the base, respectively. O<sub>2</sub> was identified
to be crucial to the formation of oxetane and α-hydroxylmalonate
derivatives.