10.1021/jo202324f.s001 Liang-Qiu Lu Liang-Qiu Lu Zhi-Hui Ming Zhi-Hui Ming Jing An Jing An Chao Li Chao Li Jia-Rong Chen Jia-Rong Chen Wen-Jing Xiao Wen-Jing Xiao Enantioselective Cascade Reactions of Stable Sulfur Ylides and Nitroolefins through an Axial-to-Central Chirality Transfer Strategy American Chemical Society 2012 cycloaddition Transfer sulfide enantioenriched enantioselective Stable Sulfur Ylides transfer synthetically annulation chirality stereoselectivitie Enantioselective Cascade Reactions strategy stereocontroller heterocycle Chirality pharmaceutically StrategyAn Nitroolefin sulfur ylides chiral yield cascade e.r oxazolidinone d.r nitroolefin 2012-01-20 00:00:00 Dataset https://acs.figshare.com/articles/dataset/Enantioselective_Cascade_Reactions_of_Stable_Sulfur_Ylides_and_Nitroolefins_through_an_Axial_to_Central_Chirality_Transfer_Strategy/2557540 An enantioselective [4 + 1] annulation/rearrangement cascade of stable sulfur ylides and nitroolefins has been developed through an efficient axial-to-central chirality transfer with the use of a chiral BINOL-derived sulfide as a reliable stereocontroller. It can provide pharmaceutically and synthetically important oxazolidinones in high stereoselectivities (up to 96:4 e.r. and >95:5 d.r.). Moreover, this strategy was also successfully applied to the asymmetric [4 + 1]/[3 + 2] cycloaddition cascade of sulfur ylides with alkene-tethered nitroolefins, and the corresponding enantioenriched fused heterocycles (up to 87:13 e.r. and >95:5 d.r.) were obtained in good to excellent yields (54–95% yields).