Assembly, Two-Photon Absorption,
and Bioimaging of
Living Cells of A Cuprous Cluster
Xuchun Wang
Xiaohe Tian
Qiong Zhang
Pingping Sun
Jieying Wu
Hongping Zhou
Baokang Jin
Jiaxiang Yang
Shengyi Zhang
Chuankui Wang
Xutang Tao
Minhua Jiang
Yupeng Tian
10.1021/cm2029855.s001
https://acs.figshare.com/articles/journal_contribution/Assembly_Two_Photon_Absorption_and_Bioimaging_of_Living_Cells_of_A_Cuprous_Cluster/2541082
A novel cuprous(I) cluster Cu<sub>4</sub>I<sub>4</sub>L<sub>4</sub> (L = (<i>E</i>)-(4-diethylanilino-styryl)pyridine)
bearing
strong two-photon absorption (TPA) was obtained using a facile assembly
method, and the crystal structure has been determined. Quantum chemical
calculations using time-dependent density functional theory (TD-DFT)
reveals that the combination of the organic ligands with the three-dimensional
Cu<sub>4</sub>I<sub>4</sub> core extends the electronic delocalization
in the cluster, leading to strong two-photon absorption action. The
TPA cross sections (Φσ<sub>2</sub>) of Cu<sub>4</sub>I<sub>4</sub>L<sub>4</sub> were enhanced with increasing polarity of solvents,
which is quite different from the solvent effects on TPA in the literature.
Compared to its free ligand, the cluster Cu<sub>4</sub>I<sub>4</sub>L<sub>4</sub> exhibits larger peak TPA cross sections in the near-infrared
region, longer fluorescence lifetimes, higher quantum yield and photostability,
lower cytotoxicity, and brighter two-photon fluorescent (TPF) bioimaging.
These integrated advantages make it desirable to be applied as a two-photon
fluorescent probe for labeling the nucleic acids in live cells.
2012-03-13 00:00:00
crystal structure
Cu 4I
Cu 4I core
absorption
section
quantum chemical calculations
fluorescence lifetimes
assembly method
peak TPA
Living Cells
ligand
cluster Cu 4I exhibits
TPF