%0 Journal Article %A Bhunia, Anup %A Yetra, Santhivardhana Reddy %A Bhojgude, Sachin Suresh %A Biju, Akkattu T. %D 2012 %T Efficient Synthesis of γ-Keto Sulfones by NHC-Catalyzed Intermolecular Stetter Reaction %U https://acs.figshare.com/articles/journal_contribution/Efficient_Synthesis_of_Keto_Sulfones_by_NHC_Catalyzed_Intermolecular_Stetter_Reaction/2518048 %R 10.1021/ol301045x.s001 %2 https://acs.figshare.com/ndownloader/files/4160977 %K Stetter reaction %K Efficient Synthesis %K sulfone %K aldehyde %K NHC precursor %K right choice %X The N-heterocyclic carbene-catalyzed intermolecular Stetter reaction of aldehydes with α,β-unsaturated sulfones allows the atom-economic and selective formation of γ-keto sulfones in good yields. Key to the success of this unique transition-metal-free carbon–carbon bond-forming reaction is the right choice of the NHC precursor and base. The reaction tolerates a broad range of different aldehydes. %I ACS Publications