Reductive Eliminations from λ<sup>3</sup>-Iodanes: Understanding Selectivity and the Crucial Role of the Hypervalent Bond
Halua Pinto de Magalhães
Hans Peter Lüthi
Antonio Togni
10.1021/ol3014039.s001
https://acs.figshare.com/articles/journal_contribution/Reductive_Eliminations_from_sup_3_sup_Iodanes_Understanding_Selectivity_and_the_Crucial_Role_of_the_Hypervalent_Bond/2499598
This computational study investigates the factors governing the selectivity of the reductive eliminations from rapidly equilibrating isomeric λ<sup>3</sup>-iodanes derived from a diaryl iodonium salt and a nucleophile. The chemoselectivity is mainly determined by the partial charge at the ipso-carbon atom involved in the 3-center–4-electron bond.
2012-08-03 00:00:00
Crucial Role
Reductive Eliminations
selectivity
chemoselectivity
isomeric
iodane
Hypervalent BondThis
charge
factor
diaryl iodonium salt
nucleophile
center
equilibrating
Selectivity
reductive eliminations
Iodane
bond