%0 Journal Article
%A Kuo, Louis Y.
%A Bentley, Anne K.
%A Shari’ati, Yusef A.
%A Smith, Curtis P.
%D 2012
%T Phosphonothioate Hydrolysis
Turnover by Cp2MoCl2 and Silver Nanoparticles
%U https://acs.figshare.com/articles/journal_contribution/Phosphonothioate_Hydrolysis_Turnover_by_Cp_sub_2_sub_MoCl_sub_2_sub_and_Silver_Nanoparticles/2497108
%R 10.1021/om300251w.s001
%2 https://acs.figshare.com/ndownloader/files/4139983
%K metallocene
%K Cp 2MoCl Cp
%K Ag nanoparticle surface
%K 5H
%K phosphonothioate
%K Phosphonothioate Hydrolysis Turnover
%K DEPP
%K 31 P NMR studies
%K ion
%K hydrolysis
%K Cp 2MoCl
%X The metallocene bis(cyclopentadienyl)molybdenum(IV) dichloride
(Cp2MoCl2; Cp = η5-C5H5) is the first organometallic compound to promote the
hydrolysis of phosphonothioates with selective P–S scission
in a stoichiometric fashion. This report shows that silver nanoparticles
capped with borohydride ions promote turnover in this hydrolytic process,
as indicated by 31P NMR studies on the reaction of O,S-diethyl phenylphosphonothioate (DEPP)
with Cp2MoCl2 (pH 7). This is the first example
of the joint use of nanoparticles and molybdenum metallocenes to promote
phosphonothioate hydrolysis. Initial results indicate the turnover
may be due to free Ag+(aq) ions present in the solution
that arise either from the slow dissolution of the nanoparticles or
from interactions with the Ag nanoparticle surface.
%I ACS Publications