Ion Channel-like Crystallographic
Signatures in Modified
GuanineāPotassium/Sodium Interactions
N. Nagapradeep
Suneeta Sharma
Sandeep Verma
10.1021/cg3016518.s001
https://acs.figshare.com/articles/journal_contribution/Ion_Channel_like_Crystallographic_Signatures_in_Modified_Guanine_Potassium_Sodium_Interactions/2446048
This communication describes crystallographic details
of structures
reminiscent of ion channels, formed from regioisomeric N7 and N9 guanine-carboxylate
conjugates with potassium/sodium ions and their subsequent STM observations
on Au(111) surface. Ion channel-like crystal structures were obtained
with the observation of a notable shift in metal ion coordination
from carbonyl to carboxylate oxygen. These results are expected to
provide insight into competing sites for modified guanineāmetal
coordination, an entry into guanine-based ion channels and a route
toward guanine-functionalized surfaces.
2013-02-06 00:00:00
metal ion coordination
carboxylate oxygen
ion channels
STM observations
regioisomeric N 7